Dynamical Systems Approach to Immune Response Modeling
DSAIRM is an R package containing a set of simulation modelss (apps) that teach within-host infection dynamics and immune response modeling from a dynamical system perspective.
All models can be explored through a graphical user interface, no reading or writing code is required. Each app comes with documenation and instructions which teach important concepts of within-host and immune response modeling, and how to use simulation models to understand such concepts.
It is also possible to go beyond the graphical interface and directly access and modify all simulations to adapt them to your needs.
The best approach to use this package is to install it, load it, and start the main menu, then you are ready to go. These lines of code typed into the
R console will get you there:
install.packages('DSAIRM') library('DSAIRM') dsairmmenu()
You can also give the package a quick try online, without having to install it. I still recommend you install it like any regular R package should you decide that you want to use it. Note that I only have a free plan for shinyapps.io, where the online version is hosted. If the link fails to work it likely means I reached my maximum monthly allowed capacity. In that case, just go ahead and install the package. It’s only 3 commands to get it up and running!
For a quick introduction to the package, step-by-step instructions on getting started, and more information on the different ways you can use the package see the tutorial (vignette).
If the DSAIRM package does in any way help you with your work such that it warrants citing it in one of your papers, please cite the DSAIRM publication in BMC Immunology.
This R package is developed and maintained by Andreas Handel. A full list of contributors and a Bibtex entry for the citation can be found here. The development of this package was partially supported by NIH grant U19AI117891.